RO 46-8443

• Target :

  Endothelin Receptor

• Related Pathways :

  GPCR/G Protein

• Purity :

  0.9977

• Bioactivity :

  RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.

• Smiles :

  COc1ccc(cc1)-c1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OC[C@H](O)CO)n1

• Molecular Formula :

  C31H35N3O8S

• Molecular Weight :

  609.69

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  175556-12-4