RO 46-8443

CAT: 0931-MF-0044792-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0044792-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
175556-12-4
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Purity
0.9977
Bioactivity
RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.
Smiles
COc1ccc(cc1)-c1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OC[C@H](O)CO)n1
Molecular Formula
C31H35N3O8S
Molecular Weight
609.69
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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