Ro 46-2005

• Target:

  Endothelin Receptor

• Related Pathways:

  GPCR/G Protein

• Purity:

  0.988

• Bioactivity:

  Ro 46-2005 is a synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor, IC50: 220 nM) .

• Smiles:

  COc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCO)c1

• Molecular Formula:

  C23H27N3O6S

• Molecular Weight:

  473.54

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  150725-87-4