TFC-007

CAT: 0931-T24870-05Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0931-T24870-05Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

927878-49-7

Target

Ligands for Target Protein for PROTAC, Ligand for E3 Ligase, PGE Synthase

Related Pathways

PROTAC, Immunology/Inflammation

Purity

0.9807

Bioactivity

TFC-007 is a selective and efficient hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, suppressing inflammatory factors. It can be used to synthesize H-PGDS degrader PROTAC (H-PGDS) -1 and study cedar pollen-induced guinea pig allergic rhinitis.

Smiles

O=C(NC1=CC=C(C=C1)N2CCC(C(=O)N3CCOCC3)CC2)C4=CN=C(N=C4)OC=5C=CC=CC5

Molecular Formula

C27H29N5O4

Molecular Weight

487.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Tfc007

CAS Number	927878-49-7
PubChem CID	16040067
IUPAC Name	N-[4-[4-(morpholine-4-carbonyl)piperidin-1-yl]phenyl]-2-phenoxypyrimidine-5-carboxamide
Molecular Formula	C27H29N5O4
Molecular Weight	487.5
XLogP	2.6
Topological Polar Surface Area	96.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Heavy Atom Count	36
Formal Charge	0
Complexity	703

SMILES

C1CN(CCC1C(=O)N2CCOCC2)C3=CC=C(C=C3)NC(=O)C4=CN=C(N=C4)OC5=CC=CC=C5

InChI

InChI=1S/C27H29N5O4/c33-25(21-18-28-27(29-19-21)36-24-4-2-1-3-5-24)30-22-6-8-23(9-7-22)31-12-10-20(11-13-31)26(34)32-14-16-35-17-15-32/h1-9,18-20H,10-17H2,(H,30,33)

InChIKey

NLSSUSRERAMBTA-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 927878-49-7

CID: 16040067

Formula: C27H29N5O4

MW: 487.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	487.5
XLogP3	2.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	487.22195442
Monoisotopic Mass	487.22195442
Topological Polar Surface Area	96.9 Å²
Heavy Atom Count	36
Formal Charge	0
Complexity	703
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

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T10393-01	AT-007
T203062-01	LZ-007
T205496-01	ALT-007
T86112-01	CXF-007
T28093-01	MPX-007
T74755-01	TUS-007
T85316-01	ADT-007
T38008	KBC-007
T8838-01	CCI-007
T26141-01	RS 61756-007

Alternative Products

Catalog	Name
HY-110167	TFC 007
562550	TFC-007
408072	AT-007
BA5761-5	ADT-007
HY-170794-01	ALT-007
HY-16633	ELND 007
452916-01	JWH-007
MBS5816693	TUS-007
MBS5798767	KBC-007
A22588-100	AT-007 100mg

TFC-007

Chemical Information

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