KBC-007

CAT: 0931-T38008Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0931-T38008Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1037297-61-2

Target

Others

Related Pathways

Others

Bioactivity

KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer) . It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the survival rate of mice immunized with the inactivated influenza A virus A/PR/8/34 in a model of influenza infection.

Smiles

CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@H](CO[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)NC(=O)CCCCCCCN(CCCCCCC)CCCCCCC

Molecular Formula

C46H92N2O9

Molecular Weight

817.247

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BA5761-5	ADT-007
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A22588-100	AT-007 100mg
A22588-10	AT-007 10mg
GTR19154739-01	CCI 007

KBC-007

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