ALT-007

• Target :

  Acyltransferase

• Related Pathways :

  Metabolism

• Bioactivity :

  ALT-007 is an orally bioavailable inhibitor of serine palmitoyltransferase (SPT), the rate-limiting enzyme in de novo ceramide synthesis. In murine models of age-related sarcopenia, ALT-007 effectively restores muscle mass and function impaired by aging. Additionally, ALT-007 may enhance protein homeostasis in Caenorhabditis elegans and in mouse models of aging and age-associated diseases, acting as a ceramide inhibitor.

• Smiles :

  O=C(NC1C2=C(C=NN2C(C)C)N(C(=O)C3=CN=C(OC)C(OC)=C3)CC1)C=4C=CC=CC4OC(F)(F)F

• Molecular Formula :

  C25H26F3N5O5

• Molecular Weight :

  533.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2035010-37-6