(±) -AMG 487

• Target:

  CXCR|||Others

• Related Pathways:

  Autophagy|||Immunology/Inflammation|||GPCR/G Protein|||Others

• Bioactivity:

  AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively) .

• Smiles:

  CCOC1=CC=C (N2C (C (N (C (CC3=CC=C (OC (F) (F) F) C=C3) =O) CC4=CN=CC=C4) C) =NC5=C (C2=O) C=CC=N5) C=C1

• Molecular Formula:

  C32H28F3N5O4

• Molecular Weight:

  603.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C