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AST 487

CAT: 0931-T4053-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T4053-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
630124-46-8
Target
FLT|||VEGFR|||c-RET|||c-Kit|||Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Apoptosis|||Angiogenesis
Purity
0.9956
Bioactivity
AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.
Smiles
C(C1=C(C(F)(F)F)C=C(NC(NC2=CC=C(OC=3C=C(NC)N=CN3)C=C2)=O)C=C1)N4CCN(CC)CC4
Molecular Formula
C26H30F3N7O2
Molecular Weight
529.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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