AST 487

• Target :

  FLT|||VEGFR|||c-RET|||c-Kit|||Bcr-Abl

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Apoptosis|||Angiogenesis

• Purity :

  0.9956

• Bioactivity :

  AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.

• Smiles :

  C(C1=C(C(F)(F)F)C=C(NC(NC2=CC=C(OC=3C=C(NC)N=CN3)C=C2)=O)C=C1)N4CCN(CC)CC4

• Molecular Formula :

  C26H30F3N7O2

• Molecular Weight :

  529.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  630124-46-8