AMG-119

• Description :

  AMG-119 is a humanized IgG1 monoclonal antibody that targets delta-like ligand 3 (DLL3) . AMG-119 can be used for the study of relapsed/refractory (R/R) small cell lung cancer (SCLC) . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) [1].

• UNSPSC :

  12352203

• Target :

  Notch

• Related Pathways :

  Neuronal Signaling; Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  [AMG-119]

• References & Citations :

  [1]Zhou D, et al. Clinical Pharmacology Profile of AMG 119, the First Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting Delta-Like Ligand 3 (DLL3), in Patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC) . J Clin Pharmacol. 2024 Mar;64 (3) :362-370.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Inhibitory Antibodies

• Clinical Information :

  No Development Reported