AMG-548

• Target :

  Casein Kinase|||p38 MAPK|||Wnt/beta-catenin|||TNF

• Related Pathways :

  MAPK|||Metabolism|||Apoptosis|||Stem Cells|||Cytoskeletal Signaling

• Purity :

  0.9991

• Bioactivity :

  AMG-548 is a selective and orally active p38? MAPK inhibitor (Ki = 0.5 nM), with higher selectivity than p38?, p38?, and p38?, and can also inhibit the TNF?, CK1?/?, and Wnt signalling pathways.

• Smiles :

  O=C1C(=C(N=C(NC[C@H](CC2=CC=CC=C2)N)N1C)C=3C=CN=CC3)C4=CC5=C(C=C4)C=CC=C5

• Molecular Formula :

  C29H27N5O

• Molecular Weight :

  461.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  864249-60-5