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AMG-548

CAT: 0931-T10298L-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T10298L-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
864249-60-5
Target
Casein Kinase, p38 MAPK, Wnt/beta-catenin, TNF
Related Pathways
MAPK, Metabolism, Apoptosis, Stem Cells, Cytoskeletal Signaling
Purity
0.9991
Bioactivity
AMG-548 is a selective and orally active p38α MAPK inhibitor (Ki = 0.5 nM), with higher selectivity than p38β, p38γ, and p38δ, and can also inhibit the TNFα, CK1δ/ε, and Wnt signalling pathways.
Smiles
O=C1C(=C(N=C(NC[C@H](CC2=CC=CC=C2)N)N1C)C=3C=CN=CC3)C4=CC5=C(C=C4)C=CC=C5
Molecular Formula
C29H27N5O
Molecular Weight
461.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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MBS5766035AMG-548
MBS386615-01AMG 548
HY-108642B-01AMG-548 (dihydrochloride)
MBS5806041AMG-548 hydrochloride
A10970-25AMG 548 25mg
MBS5752683AMG-548 dihydrochloride
HY-108642AAMG-548 (hydrochloride)
A10970-100AMG 548 100mg
A10970-50AMG 548 50mg
A10970-10AMG 548 10mg

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