BMS-P5 free base

• Target:

  PAD

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9996

• Bioactivity:

  BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor that blocks the formation of Neutrophil Extracellular Traps and delays the progression of multiple myeloma. Administration of BMS-P5 to multiple myeloma-bearing mice delays symptom onset and disease progression. Targeting PAD4 may be beneficial for treating multiple myeloma.

• Smiles:

  COc1cc (cc2nc (-c3cc4cccnc4n3CC3CC3) n (C) c12) C (=O) N1C[C@H] (N) CC[C@@H]1C

• Molecular Formula:

  C27H32N6O2

• Molecular Weight:

  472.58

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1550371-22-6