BMS-604992 (free base)

• UNSPSC Description:

  BMS-604992 (EX-1314) free base is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. BMS-604992 free base demonstrates high-affinity binding (ki=2.3 nM) and potent functional activity (EC50=0.4 nM). BMS-604992 free base can stimulate food intake in rodents[1].

• Target Antigen:

  GHSR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/bms-604992-free-base.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OCC1=CC=CC2=NN=C([C@H](NC(C(C)(N)C)=O)COCC3=CC=CC=C3)N12)N(CC(N)=O)C

• Molecular Weight:

  497.55

• References & Citations:

  [1]Charoenthongtrakul S, et, al. Enhanced gastrointestinal motility with orally active ghrelin receptor agonists. J Pharmacol Exp Ther. 2009 Jun;329(3):1178-86.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  760944-56-7