BRD7-IN-1

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Chromatin/Epigenetic

• Purity:

  0.9895

• Bioactivity:

  BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 via linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively [1].

• Smiles:

  Cl.Cl.COc1cc(cc(OC)c1CN1CCNCC1)-c1cn(C)c(=O)c2cnccc12

• Molecular Formula:

  C22H28Cl2N4O3

• Molecular Weight:

  467.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2448414-48-8