BRD7-IN-3

• UNSPSC Description:

  BRD7-IN-3 (compound 1-78) is a dual inhibitor of bromodomain-containing proteins BRD7/BRD9 with IC50s of 1.6 μM and 2.7 μM respectively[1].

• Target Antigen:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/brd7-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC(N(C2=C1C=CC(C3=CC=C(N=C3C)OC)=C2)C)=O

• Molecular Weight:

  294.35

• References & Citations:

  [1]Ordonez-Rubiano SC, et al. Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer. J Med Chem. 2023 Aug 24;66(16):11250-11270..

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3032601-04-7