BRD7-IN-3

• Description :

  BRD7-IN-3 (compound 1-78) is a dual inhibitor of bromodomain-containing proteins BRD7/BRD9 with IC50s of 1.6 μM and 2.7 μM respectively[1].

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/brd7-in-3.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CC(N(C2=C1C=CC(C3=CC=C(N=C3C)OC)=C2)C)=O

• Molecular Formula :

  C18H18N2O2

• Molecular Weight :

  294.35

• References & Citations :

  [1]Ordonez-Rubiano SC, et al. Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer. J Med Chem. 2023 Aug 24;66 (16) :11250-11270..

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3032601-04-7]