GNE-616

• Target:

  Sodium Channel|||Others

• Related Pathways:

  Membrane transporter/Ion channel|||Others

• Bioactivity:

  GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype-selective Nav1.7 inhibitor [Ki: 0.79 nM, Kd: 0.38 nM for hNav1.7] for the treatment of chronic pain.

• Smiles:

  C (F) (F) (F) [C@@H]1C[C@@H] (N (CC1) [C@@H]2C=3C (=CC (S (NC=4C=CN=CN4) (=O) =O) =C (F) C3) OCC2) C5=CC=CC=N5

• Molecular Formula:

  C24H23F4N5O3S

• Molecular Weight:

  537.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2349371-81-7