GNE-616

• Target :

  Sodium Channel|||Others

• Related Pathways :

  Membrane transporter/Ion channel|||Others

• Bioactivity :

  GNE-616 is a highly potent, metabolically stable, orally bioavailable, and subtype-selective Nav1.7 inhibitor [Ki: 0.79 nM, Kd: 0.38 nM for hNav1.7] for the treatment of chronic pain.

• Smiles :

  C(F)(F)(F)[C@@H]1C[C@@H](N(CC1)[C@@H]2C=3C(=CC(S(NC=4C=CN=CN4)(=O)=O)=C(F)C3)OCC2)C5=CC=CC=N5

• Molecular Formula :

  C24H23F4N5O3S

• Molecular Weight :

  537.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2349371-81-7