(S) -3-Hydroxy Midostaurin

• Target:

  FLT|||Drug Metabolite|||Others

• Related Pathways:

  Angiogenesis|||Others|||Metabolism|||Tyrosine Kinase/Adaptors

• Bioactivity:

  (S) -3-Hydroxy Midostaurin is a potent inhibitor of kinases (IC50 of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et) ) .

• Smiles:

  C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)[C@H](O)NC6=O)C=8C(N5[C@](O1)(C[C@@H](N(C(=O)C9=CC=CC=C9)C)[C@H]2OC)[H])=CC=CC8

• Molecular Formula:

  C35H30N4O5

• Molecular Weight:

  586.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  945260-14-0