Midostaurin

CAT: 0931-T3211-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T3211-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
120685-11-2
Target
PKC|||c-Kit|||VEGFR|||Apoptosis|||NO Synthase
Related Pathways
Cytoskeletal Signaling|||Angiogenesis|||Apoptosis|||Chromatin/Epigenetic|||Immunology/Inflammation|||Tyrosine Kinase/Adaptors
Purity
>99.99%
Bioactivity
PKC412 (Midostaurin (PKC412) ; CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.
Smiles
COC1C(CC2OC1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1
Molecular Formula
C35H30N4O4
Molecular Weight
570.64
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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