3-Hydroxy Midostaurin-D5

CAT: 0931-T19119-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T19119-01Size:100 mg
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Bioactivity
3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9.8 ?M in culture medium and plasma) .
Smiles
OC1NC(C2=C1C(C3=C4C=CC=C3)=C5N4[C@]6(O[C@@H](N7C5=C2C8=C7C=CC=C8)C[C@H]([C@H]6OC)N(C(C(C([2H])=C9[2H])=C(C([2H])=C9[2H])[2H])=O)C)C)=O
Molecular Formula
C35H25D5N4O5
Molecular Weight
591.67
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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