PRMT5-IN-1

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  PRMT5-IN-1 is a covalent inhibitor of protein arginine methyltransferase 5 (PRMT5) (IC50 of 11 nM for PRMT5/MEP50) .

• Smiles:

  O[C@H]1[C@H](N2C3=C(C=4N(C=N3)C(O)CN4)C=C2)O[C@]([C@H](O)C5=CC=C(Cl)C=C5)([C@H]1O)[H]

• Molecular Formula:

  C19H19ClN4O5

• Molecular Weight:

  418.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2366149-83-7