APX-115 free base

CAT: 0931-MF-0004445-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0004445-01Size:1 mg
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
1270084-92-8
Target
NADPH-oxidase|||NADPH
Related Pathways
Immunology/Inflammation|||Metabolism
Purity
0.9903
Bioactivity
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 ?M, 0.57 ?M, and 0.63 ?M for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury.
Smiles
CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1
Molecular Formula
C17H17N3O
Molecular Weight
279.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Popular Products