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APX-115 free base

CAT: 0931-T10353-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T10353-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1270084-92-8
Target
NADPH-oxidase, NADPH
Related Pathways
Immunology/Inflammation, Metabolism
Purity
0.9903
Bioactivity
APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with inhibition constants (Kis) of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4, respectively, and it effectively prevents kidney injury.
Smiles
CCCc1c(O)n(nc1-c1ccccc1)-c1ccccn1
Molecular Formula
C17H17N3O
Molecular Weight
279.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C