KG-548

• Target:

  HIF/HIF Prolyl-Hydroxylase|||Microtubule Associated|||HIF

• Related Pathways:

  Cytoskeletal Signaling|||Metabolism|||Chromatin/Epigenetic|||Angiogenesis

• Purity:

  0.9962

• Bioactivity:

  KG-548 is a dual inhibitor of ARNT/TACC3 and HIF-1?, binding to the ?-fold surface involved in HIF-2 dimerization and coactivator recruitment, inhibiting lactate production and useful in cancer research.

• Smiles:

  FC(F)(F)C1=CC(=CC(=C1)C(F)(F)F)C2=NN=NN2

• Molecular Formula:

  C9H4F6N4

• Molecular Weight:

  282.15

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  175205-09-1