Trichostatin A,HDAC inhibitor

Research Area s

Cancer , Apoptosis , Cancer Growth Inhibitors , HDAC Inhibitors
Category

Small Molecules
Product Type

Inhibitor
CAS No

58880-19-6
MolecularFormula

C17H22N2O3
Molecular Weight

302.37
Purity

>98%
Solubility

Soluble to 10 mM in ethanol and to 50 mM in DMSO
Appearance

Beige Solid
Storage Temperature

-20°C
Shipping Temperature

Shipped Ambient
Description

Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

Identity

HGNC:14063
Gene

HDAC4
Long gene name

histone deacetylase 4
Synonyms gene
- BDMR
Synonyms gene name
- brachydactyly-mental retardation syndrome
Synonyms
- KIAA0288
- HDAC-A
- HDACA
- HD4
- HA6116
- HDAC-4
GenBank acession
- AB006626
Locus

2q37.3
Discovery year

2000-11-28
Entrez gene record

9759
Pubmed identfication
RefSeq identity
- NM_006037
Classification
- Histone deacetylases, class IIA
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000133344