- Catalog number6448-10
- Product nameHuman CellExp™ FGF-2/FGF-basic, Human Recombinant
- Size10 ug
- PriceAsk For Price
- SynonymsHuman Cellexp Human Recombinant FGF-basic
- Alternative namesProstatropin, HBGH-2, HBGF-2, FGF-2, FGF-b.
- DescriptionA growth factor involved in angiogenesis, wound healing and embryonic development
- RecombinantYes
- SourceHuman cell expressed
- Purity by SDS PAGE≥95%
- AssaySDS-PAGE
- Endotoxin Level< 1.0 EU per 1 ug of protein
- Biological activityED₅₀ is typically 0.1 to 0.5 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of the 3T3 cell line.
- Results0.1 to 0.5 ng/ml
- Molecular Weight17 kDa, monomer, non-glycosylated
- Storage Temp-20°C
- Shippinggel pack
- Shelf Life12 months
- AppearanceLyophilized
- Physical form descriptionLyophilized from a PBS solution.
- Reconstitution InstructionsReconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.
- Background InformationFGF-basic is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.
- HandlingCentrifuge the vial prior to opening.
- UsageFor Research Use Only! Not to be used in humans
- Datasheet
- Gene targetCellExp™ FGF-2/FGF
- Identity:HGNC:8053
- Gene:NUDT6
- Long gene name:nudix hydrolase 6
- Synonyms gene name:nudix (nucleoside diphosphate linked moiety X)-type motif 6
- Synonyms:gfg-1gfgFGF2ASFGF-AS
- Discovery year:1999-09-03
- Entrez gene record:11162
- Pubmed identification:7984147, 10022609
- RefSeq identity:NM_007083
- Classification:Nudix hydrolase family
- VEGA ID:OTTHUMG00000039507
- Identity:HGNC:3676
- Gene:FGF2
- Long gene name:fibroblast growth factor 2
- Synonyms gene name:fibroblast growth factor 2 (basic)
- Discovery year:1986-01-01
- Entrez gene record:2247
- Pubmed identification:9925931
- RefSeq identity:NM_002006
- Classification:Fibroblast growth factor family, Receptor ligands
- VEGA ID:OTTHUMG00000039506
- Identity:HGNC:3682
- Gene:FGF4
- Long gene name:fibroblast growth factor 4
- Synonyms gene name:heparin secretory transforming protein 1
- Synonyms:K-FGFHBGF-4HSTHST-1KFGF
- Discovery year:1988-04-20
- Entrez gene record:2249
- Pubmed identification:1611909
- RefSeq identity:NM_002007
- Classification:Fibroblast growth factor family, Receptor ligands
- VEGA ID:OTTHUMG00000167887
- Identity:HGNC:3665
- Gene:FGF1
- Long gene name:fibroblast growth factor 1
- Synonyms gene name:fibroblast growth factor 1 (acidic)
- Synonyms:AFGFECGFECGFAECGFBHBGF1ECGF-betaFGF-alphaGLIO703
- Discovery year:1986-01-01
- Entrez gene record:2246
- Pubmed identification:1697263, 3523756
- RefSeq identity:NM_000800
- Classification:Fibroblast growth factor family, Receptor ligands
- VEGA ID:OTTHUMG00000059703
- Identity:HGNC:3670
- Gene:FGF13
- Long gene name:fibroblast growth factor 13
- Synonyms gene name:long intergenic non-protein coding RNA 889
- Synonyms:FHF2FGF2FLJ30672
- Discovery year:1996-12-16
- Entrez gene record:2258
- Pubmed identification:8790420
- RefSeq identity:NM_004114
- Classification:Fibroblast growth factor family, MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000022532
- Identity:HGNC:31639
- Gene:MIR7-2
- Long gene name:microRNA 7-2
- Synonyms:hsa-mir-7-2
- Discovery year:2004-04-23
- Entrez gene record:407044
- RefSeq identity:NR_029606
- Classification:MicroRNA MIR7 family
- Identity:HGNC:32051
- Gene:MIR329-2
- Long gene name:microRNA 329-2
- Synonyms:hsa-mir-329-2
- Discovery year:2005-07-11
- Entrez gene record:574409
- RefSeq identity:NR_029968
- Classification:MicroRNA MIR329 family
- Identity:HGNC:32091
- Gene:MIR512-2
- Long gene name:microRNA 512-2
- Synonyms:hsa-mir-512-2
- Discovery year:2005-07-15
- Entrez gene record:574459
- RefSeq identity:NR_030181
- Classification:MicroRNA MIR506 family
- Gene symbolFGF18, FGF17, NUDT6, FGF2, FGF4, FGF1, FGF13, MIR7-2, MIR329-2, MIR512-2
- Short nameCellExp™ FGF-2/FGF- , Recombinant
- technique filter
- Recombinant
- TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
- Alternative techniquerec
Gene info
Gene info
Gene info
Gene info
Locus Specific Databases:LRG_1185