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3-Deazaneplanocin A

CAT: 0026-2060-250Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0026-2060-250Size:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A lysine methyltransferase EZH2 (KMT63) inhibitor. DZNep is a selective inhibitor of trimethylation of lysine 27 on histone H3 (H3K27me3) and lysine 20 on histone H4 (H4K20me3). DZNep treatment of cultured human AML cells induces increased expression of the cell-cycle regulators p21, p27, and FBXO32, leading to cell cycle arrest and apoptosis.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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