2-Hexyl-4-Pentynoic Acid

CAT: 0026-B2834-100Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0026-B2834-100Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

2-Hexyl-4-Pentynoic Acid is an inhibitor of histone deacetylases (HDACs). It is a derivative of Valproic acid. It inhibits HDAC activity with an IC₅₀ of 13 μM, compared to an IC₅₀ of 398 μM for Valproic acid. It induces histone hyperacetylation at a concentration of 5 μM in cerebellar granule cells and increases HSP70-1a and HSP70-1b mRNA levels at 50 μM. It is neuroprotective against glutamate-induced excitotoxicity.

Shipping Conditions

Storage Conditions

-20ºC

Shelf Life

24months

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T21551-01	2-hexyl-4-Pentynoic Acid
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2-Hexyl-4-Pentynoic Acid

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