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17-Hydroxyprogesterone ELISA Kit

CAT: 0026-E4345-100Size: 100 AssaysDry Ice: NoHazardous: No
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CAT#:0026-E4345-100Size:100 Assays
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Description
The adrenal glands, ovaries, testes, and placenta produce 17-hydroxyprogesterone. It is hydroxylated at the 11 and 21 position to produce cortisol. Deficiency of either 11- or 21-hydroxylase results in decreased cortisol synthesis, and feedback inhibition of adrenocorticotropic hormone (ACTH) secretion is lost. Consequent increased pituitary release of ACTH will increase production of 17-HOP. But, if 17-alpha-hydroxylase (which allows formation of 17-HOP from progesterone) or 3ß-hydroxysteroid dehydrogenase type 2 (which allows formation of 17-hydroxyprogesterone formation from 17-hydroxypregnenolone) are deficient, 17-HOP levels are low with possible increase in progesterone or pregnenolone respectively. BioVision’s 17-Hydroxyprogesterone ELISA kit is a competitive ELISA assay for the quantitative measurement of 17-Hydroxyprogesterone in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue culture media samples.
CAS Number
7732-18-5
Reactivity
Universal
Applications
This ELISA kit is used for quantitative measurement of human total 17-HOP in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue
Detection Method
Absorbance (450 nm)
Features & Benefits
Easy, convenient and time-saving method to measure the level of 17-HOP in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue. Detection Range: 6000 – 24.69 pg/ml Sensitivity: < 20.3 pg/ml Detection Limit: 15.4 pg/ml
Shipping Conditions
gel pack
Storage Conditions
4°C
Shelf Life
6 months

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