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1-NM-PP1

CAT: 0026-B2346-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2346-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
1NM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors. Inhibits multiple tyrosine kinase targets, such as v-Src (IC50 = 1 μM), c-Fyn (IC50 = 0.6 μM), c-Abl (IC50 = 0.6 μM), CDK2 (IC50: 18 μM), and CaMK II (IC50 = 22 μM). Addiitonally, 1-NM-PP1 is reported to be a potent and specific inhibitor of TrkB-F616A and TrkA-F592A signaling (IC50 values ~ 3 nM).
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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