CREB Blocking Peptide
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Catalog number3360RBP-50
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PricePlease ask
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Size50 μg
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Antibody TargetCREB
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AccessionEDL98880
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Gene ID81646
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AppearanceColorless liquid
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Concentration0.5 mg/ml
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Formulation50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
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Application UsageTranscription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
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Storage Temp-20 °C
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Shippinggel pack
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Shelf Life12 months
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Western Blot WBVerified
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HandlingThe peptide solution should be gently mixed before use.
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Research UseFor Rersearch Use Only! Not to be used in humans.
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TestYou can block the antibody by the specific target amino acid sequence of peptide.
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Propertiesblocking peptide
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DescriptionPeptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
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Gene target
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Gene symbolCREB3L3, ATF4
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Short nameCREB Blocking Peptide
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Techniqueblocking peptide, Blocking, peptide, blocking peptides, Biovision made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
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Alternative nameCREB inhibiting short protein sequence
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Alternative techniquecontrol, peptides
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Gene info
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Identity
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Gene
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Long gene namecAMP responsive element binding protein 3 like 3
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Synonyms
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Synonyms name
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Locus
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Discovery year2003-12-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CREB3 transcription factor family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameactivating transcription factor 4
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Synonyms gene
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Synonyms gene name
- activating transcription factor 4 (tax-responsive enhancer element B67)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1992-06-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basic leucine zipper proteins
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VEGA ID