- Catalog number3360RBP-50
- Product nameCREB Blocking Peptide
- Size50 μg
- PriceAsk For Price
- Antibody TargetCREB
- AccessionEDL98880
- Gene ID81646
- AppearanceColorless liquid
- Concentration0.5 mg/ml
- Formulation50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
- Application UsageTranscription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
- Storage Temp-20 °C
- Shippinggel pack
- Shelf Life12 months
- Western Blot WBVerified
- HandlingThe peptide solution should be gently mixed before use.
- DataSheet Link
- Research UseFor Rersearch Use Only! Not to be used in humans.
- Gene targetCREB
- Identity:HGNC:18855
- Gene:CREB3L3
- Long gene name:cAMP responsive element binding protein 3 like 3
- Synonyms:CREB-HCREBH
- Discovery year:2003-12-09
- Entrez gene record:84699
- Pubmed identification:11353085
- RefSeq identity:NM_032607
- Classification:CREB3 transcription factor family
- VEGA ID:OTTHUMG00000181846
- Identity:HGNC:786
- Gene:ATF4
- Long gene name:activating transcription factor 4
- Synonyms gene name:activating transcription factor 4 (tax-responsive enhancer element B67)
- Synonyms:TAXREB67CREB-2
- Discovery year:1992-06-09
- Entrez gene record:468
- Pubmed identification:1847461, 1534408
- RefSeq identity:NM_001675
- Classification:Basic leucine zipper proteins
- VEGA ID:OTTHUMG00000151099
- Gene symbolCREB3L3, ATF4
- Short nameCREB Blocking Peptide
- technique filter
- blocking peptide
- Blocking
- peptide
- Techniqueblocking peptide, Blocking, peptide, blocking peptides, Biovision made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
- Alternative techniquecontrol, peptides