DKM 2-93

• Description :

  DKM 2-93 is a relatively selective inhibitor of UBA5 with an IC50 of 430 μM.

• CAS Number :

  [65836-72-8]

• UNSPSC :

  12352005

• Hazard Statement :

  H301, H311, H331, H341

• Target :

  E1/E2/E3 Enzyme

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/DKM_2-93.html

• Purity :

  98.76

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(NCC1=CC=C(OC)C(OC)=C1)CCl

• Molecular Formula :

  C11H14ClNO3

• Molecular Weight :

  243.69

• Precautions :

  H301, H311, H331, H341

• References & Citations :

  [1]Roberts AM, et al. Chemoproteomic Screening of Covalent Ligands Reveals UBA5 As a Novel Pancreatic Cancer Target. ACS Chem Biol. 2017 Apr 21;12 (4) :899-904.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported