MERTK Extracellular Domain Human Recombinant

• Description:

  MERTK Extracellular Domain Human Recombinant _x000D_ Catalog number: B2016935_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 10 µg_x000D_ Molecular Weight or Concentration: 60 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: MER, c-MER, Proto-oncogene c-Mer, Receptor Tyrosine Kinase MerTK, RP38, Tyrosine-protein Kinase Mer_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Garbin U, Baggio E, Stranieri C, Pasini A, Manfro S, Mozzini C, Vallerio P, Lipari G, Merigo F, Guidi G, Cominacini L, Fratta Pasini A. Expansion of necrotic core and shedding of Mertk receptor in human carotid plaques: a role for oxidized polyunsaturated fatty acids? Cardiovasc Res. 2013 Jan 1;97(1):125-33._x000D_ 2: Zhou J, Yang A, Wang Y, Chen F, Zhao Z, Davra V, Suzuki-Inoue K, Ozaki Y, Birge RB, Lu Q, Wu Y. Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation Cell Commun Signal. 2018 Dec 12;16(1):98._x000D_ 3: Miller MA, Sullivan RJ, Lauffenburger DA. Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer Clin Cancer Res. 2017 Feb 1;23(3):623-629._x000D_ 4: Ling L, Kung HJ. Mitogenic signals and transforming potential of Nyk, a newly identified neural cell adhesion molecule-related receptor tyrosine kinase Mol Cell Biol. 1995 Dec;15(12):6582-92._x000D_ 5: Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K. Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases J Biol Chem. 1996 Nov 22;271(47):30022-7._x000D_ 6: Funakoshi H, Yonemasu T, Nakano T, Matumoto K, Nakamura T. Identification of Gas6, a putative ligand for Sky and Axl receptor tyrosine kinases, as a novel neurotrophic factor for hippocampal neurons J Neurosci Res. 2002 Apr 15;68(2):150-60._x000D_ 7: Mark MR, Chen J, Hammonds RG, Sadick M, Godowsk PJ. Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl J Biol Chem. 1996 Apr 19;271(16):9785-9._x000D_ 8: Fan J, Yu Y, Yan L, Yuan Y, Sun B, Yang D, Liu N, Guo J, Zhang J, Zhao X. GAS6-based CAR-T cells exhibit potent antitumor activity against pancreatic cancer J Hematol Oncol. 2023 Jul 20;16(1):77._x000D_ 9: Caberoy NB, Alvarado G, Li W. Tubby regulates microglial phagocytosis through MerTK J Neuroimmunol. 2012 Nov 15;252(1-2):40-8._x000D_ 10: Prieto AL, Lai C. The TAM Subfamily of Receptor Tyrosine Kinases: The Early Years Int J Mol Sci. 2024 Mar 16;25(6):3369. _x000D_ _x000D_ Products Related to MERTK Extracellular Domain Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2016935 (10 µg)_x000D_ MERTK Extracellular Domain Human Recombinant is a high receptor tyrosine kinase that plays a role in various cellular processes, including phagocytosis and cell survival. The extracellular domain of MERTK is involved in binding to ligands that activate downstream signaling pathways. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3