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MTRP-2 (180-188)

CAT: 0804-HY-P1827-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1827-01Size:1 mg
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Description
MTRP-2 (180-188) is a murine tyrosinase-related protein 2 (TRP-2) -derived peptide, corresponding to residues 180-188. TRP-2 (180-188) is identified as the major reactive epitope within TRP-2 recognized by anti-B16 CTLs[1].
CAS Number
219312-69-3
UNSPSC
12352209
Target
Tyrosinase
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mtrp-2-180-188.html
Purity
99.61
Solubility
DMSO : ≥ 50 mg/mL|H2O : 33.33 mg/mL (ultrasonic; adjust pH to 12 with 1M NaOH)
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C(C)C)NC([C@H](CC3=CC=CC=C3)NC([C@H](CC4=CC=CC=C4)NC([C@H](CC(O)=O)NC([C@H](CC5=CC=C(O)C=C5)NC([C@H](C(C)C)NC([C@H](CO)N)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C61H78N10O14
Molecular Weight
1175.33
References & Citations
[1]Bloom MB, et al. Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma. J Exp Med. 1997 Feb 3;185 (3) :453-9.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

Chemical Information

CID 9963581
CAS Number219312-69-3
PubChem CID9963581
IUPAC Name(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylpentanoic acid
Molecular FormulaC61H78N10O14
Molecular Weight1175.3
XLogP2.4
Topological Polar Surface Area390
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count15
Rotatable Bond Count32
Heavy Atom Count85
Formal Charge0
Complexity2230
SMILES
CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CO)N
InChI
InChI=1S/C61H78N10O14/c1-33(2)25-49(61(84)85)69-56(79)47(29-39-31-63-43-20-14-13-19-41(39)43)68-60(83)52(35(5)6)71-58(81)46(27-37-17-11-8-12-18-37)65-54(77)44(26-36-15-9-7-10-16-36)64-57(80)48(30-50(74)75)66-55(78)45(28-38-21-23-40(73)24-22-38)67-59(82)51(34(3)4)70-53(76)42(62)32-72/h7-24,31,33-35,42,44-49,51-52,63,72-73H,25-30,32,62H2,1-6H3,(H,64,80)(H,65,77)(H,66,78)(H,67,82)(H,68,83)(H,69,79)(H,70,76)(H,71,81)(H,74,75)(H,84,85)/t42-,44-,45-,46-,47-,48-,49-,51-,52-/m0/s1
InChIKey
DONZTCDLTFZGMF-UKTPXDMFSA-N
Chemical Structure
2D Structure
2D structure of CID 9963581
CAS: 219312-69-3
CID: 9963581
Formula: C61H78N10O14
MW: 1175.3
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight1175.3
XLogP32.4
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count15
Rotatable Bond Count32
Exact Mass1174.56989720
Monoisotopic Mass1174.56989720
Topological Polar Surface Area390 Ų
Heavy Atom Count85
Formal Charge0
Complexity2230
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes