NXN-188

• Description :

  NXN-188 is a combined nNOS inhibitor and an agonist of 5HT-1B/1D receptor. NXN-188 can be studied in research on migraine[1].

• UNSPSC :

  12352005

• Target :

  5-HT Receptor; NO Synthase

• Related Pathways :

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Smiles :

  N=C(C1=CC=CS1)NC2=CC3=C(NC=C3C4=CCN(C)CC4)C=C2

• Molecular Formula :

  C19H20N4S

• Molecular Weight :

  336.45

• References & Citations :

  [1]Hougaard, A., et al., (2013) . The nitric oxide synthase inhibitor and serotonin-receptor agonist NXN-188 during the aura phase of migraine with aura: A randomized, double-blind, placebo-controlled cross-over study. Scandinavian journal of pain, 4 (1), 48-52.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• CAS Number :

  [915036-97-4]