BTA-188

CAT: 0804-HY-162022-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-162022-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTA-188, a pyridazinyl oxime ether, is an orally active, potent inhibitor of rhinoviruses (HRV) and enterovirus (EV) 71 in vitro. BTA-188 inhibits HRV-2 replication with an IC50 of 0.8 nM and an IC90 of 11 nM. BTA-188 inhibits enterovirus with an IC50 of 82 and an IC90 of 109 nM. BTA-188 is a potential chemotherapeutic agent for infections caused by the viruses in the Picornaviridae[1].
CAS Number
[314062-80-1]
UNSPSC
12352005
Target
Enterovirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bta-188.html
Smiles
CCO/N=C/C(C=C1)=CC=C1OCCC(CC2)CCN2C3=NN=C(C)C=C3
Molecular Formula
C21H28N4O2
Molecular Weight
368.47
References & Citations
[1]D L Barnard, et al. In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity. Antimicrob Agents Chemother. 2004 May;48 (5) :1766-72.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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