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ERK-IN-8

CAT: 0804-HY-164151Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164151Size:1 Each
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Description
ERK-IN-8 (compound I-1) is an aniline pyrimidine derivative that acts as an ERK inhibitor. ERK-IN-8 has a strong inhibitory effect on ERK2 in vitro (IC50≤50 nM) . ERK-IN-8 can be used in cancer research[1].
CAS Number
2226293-75-8
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erk-in-8.html
Smiles
C=CC(NC1=CC(NC2=NC=CC(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(C)CCNC)=O
Molecular Formula
C26H29N7O2
Molecular Weight
471.55
References & Citations
[1]Jianqiu Tang, et al. Aniline pyrimidine derivative as ERK inhibitor.CN107973783A.2016-10-21
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK2