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ERK-CLIPTAC

CAT: 0804-HY-153735Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153735Size:1 Each
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Description
ERK-CLIPTAC is a PROTAC molecule that triggers the degradation of ERK[1].
CAS Number
2087490-46-6
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/erk-cliptac.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCC#CC1=NC=CC(NC2=NC=C(C(NC3=C(NC(C=C)=O)C=CC=C3)=N2)Cl)=C1)OC4CCC5=C(C)NN=C(C5CCC4)C6=CC=C(CNC(CCCCCOC7=CC=CC(C(N8C9C(NC(CC9)=O)=O)=O)=C7C8=O)=O)C=C6
Molecular Formula
C60H61ClN12O9
Molecular Weight
1129.65
References & Citations
[1]Honorine Lebraud, et al. Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras. ACS Cent Sci. 2016 Dec 28;2 (12) :927-934.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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