ERK-CLIPTAC

• Description :

  ERK-CLIPTAC is a PROTAC molecule that triggers the degradation of ERK[1].

• CAS Number :

  [2087490-46-6]

• UNSPSC :

  12352005

• Target :

  PROTACs

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/erk-cliptac.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCCC#CC1=NC=CC(NC2=NC=C(C(NC3=C(NC(C=C)=O)C=CC=C3)=N2)Cl)=C1)OC4CCC5=C(C)NN=C(C5CCC4)C6=CC=C(CNC(CCCCCOC7=CC=CC(C(N8C9C(NC(CC9)=O)=O)=O)=C7C8=O)=O)C=C6

• Molecular Formula :

  C60H61ClN12O9

• Molecular Weight :

  1129.65

• References & Citations :

  [1]Honorine Lebraud, et al. Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras. ACS Cent Sci. 2016 Dec 28;2 (12) :927-934.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported