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ERK-IN-7

CAT: 0804-HY-153350Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-153350Size:1 Each
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Description
ERK-IN-7 (Example 10), an analogue of SHR2415 , is a potent ERK inhibitor with IC50 of 5 nM and 7 nM against ERK1 and ERK2, respectively[1].
CAS Number
2494010-63-6
UNSPSC
12352005
Target
ERK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erk-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C(CN1[C@@H](C3=CC(Cl)=CC=C3)CO)=CC(C4=NC(NC5=CC=NN5C)=NC=C4)=C2
Molecular Formula
C22H20ClN7O2
Molecular Weight
449.89
References & Citations
[1]Xin Li, et al. Pyrroloheterocyclic derivative, preparation method therefor, and application thereof in medicine. Patent WO2020200069A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK1; ERK2