CPN-351

CAT: 0804-HY-P10473Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-P10473Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

CPN-351 (compound 9a), a pentapeptide, is a selective antagonist of human NMUR1 with a pA2 of 7.35. The antagonistic effect of CPN-351 on human NMUR1 is 10 times higher than that on NMUR2. CPN-351 can be used in the study of inflammation[1].

CAS Number

3057171-63-5

UNSPSC

12352209

Target

Neuromedin U Receptor (NMUR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cpn-351.html

Smiles

CN([C@H](C(N[C@@](CC1=CC=CC=C1)(C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)C)=O)CC3=CNC4=C3C=CC=C4)C(CC5=CC=CS5)=O

Molecular Formula

C45H61N13O6S

Molecular Weight

912.11

References & Citations

[1]akayama K, et al. Discovery of a Pentapeptide Antagonist to Human Neuromedin U Receptor 1. ACS Med Chem Lett. 2024 May 24;15 (6) :885-891.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

NMUR1

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HY-P3134	CPN-267
HY-P3135	CPN-116
HY-131349-01	CCR4-351
HY-164404-01	NADI-351
HY-117529	BMS-351
HY-131349A-01	CCR4-351 (hydrochloride)
HY-P3134A-01	CPN-267 (TFA)
HY-W953363	CRBN ligand-351

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GTR19144533-01	CPN-351
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GTR17968154	Cpn Antibody
311949-01	CPN cat
311950-01	CPN reg
6448/25	ML 351
GTR19209000-01	BMS-351

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