CPN-267 (TFA)

• Description:

  CPN-267 (compound 7b) TFA is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 TFA suppresses body weight gain in mice and can be used for study of obesity[1].

• UNSPSC:

  12352209

• Target:

  Neuromedin U Receptor (NMUR)

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Purity:

  99.20

• Smiles:

  O=C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC(N)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CC2=CNC3=CC=CC=C23)NC([C@](NC(CC4=CC=CS4)=O)(C)CC5=CNC6=CC=CC=C56)=O)=O.O=C(C(F)(F)F)O.O=C(C(F)(F)F)O

• Molecular Formula:

  C54H68F6N16O12S

• Molecular Weight:

  1279.27

• References & Citations:

  [1]Takayama K, et al. Discovery of a Human Neuromedin U Receptor 1-Selective Hexapeptide Agonist with Enhanced Serum Stability [published correction appears in J Med Chem. 2017 Sep 14;60 (17) :7613.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported