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HDAC-IN-82

CAT: 0804-HY-169922Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169922Size:1 Each
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Description
HDAC-IN-82 (Compound 18b) is a histone deacetylase (HDAC) inhibitor with selective antiplasmodial and anticancer activity. HDAC-IN-82 shows potent antiproliferative activity and caspase 3/7 activation in cancer cells. HDAC-IN-82 causes hyperacetylation of histone H3 and α-tubulin[1].
UNSPSC
12352005
Target
Caspase; HDAC; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-82.html
Smiles
O=C(C1=CN=C(N2CCC(CN(C3(C(NCC4=CC=CC=C4)=O)CNCC3)C=O)CC2)N=C1)NO
Molecular Formula
C24H31N7O4
Molecular Weight
481.55
References & Citations
[1]Stopper D, et al. Multicomponent syntheses enable the discovery of novel quisinostat-derived chemotypes as histone deacetylase inhibitors. Eur J Med Chem. 2025 Jan 5;281:117045.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 7

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