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K6PC-5

CAT: 0804-HY-124042-05Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-124042-05Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
K6PC-5, a ceramide derivative, is a sphingosine kinase 1 (SPHK1) activator and elicites a rapid transient increase in intracellular calcium levels. K6PC-5 has the potential for skin diseases involving abnormal keratinocyte, and neurodegeneration and virus infection research[1][2][3].
CAS Number
756875-51-1
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Filovirus; SphK
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/k6pc-5.html
Purity
99.27
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCC(C(C(NC(CO)CO)=O)CCCCCC)=O
Molecular Formula
C19H37NO4
Molecular Weight
343.50
Precautions
H302, H315, H319, H335
References & Citations
[1]Kwon YB, et al. Novel synthetic ceramide derivatives increase intracellular calcium levels and promote epidermal keratinocyte differentiation. J Lipid Res. 2007 Sep;48 (9) :1936-43. |[2]Jong-Kyung Youm, et al. K6PC-5, a sphingosine kinase activator, induces anti-aging effects in intrinsically aged skin through intracellular Ca2+ signaling. J Dermatol Sci. 2008 Aug;51 (2) :89-102.|[3]Imre G, et al. The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection. iScience. 2021 Mar 5;24 (4) :102266.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EBOV; SphK1

Chemical Information

Dihydroxyisopropyl capryloylcaprylamide

See also: N-(1,3-Dihydroxypropyl)-2-hexyl-3-oxo-decanamide (annotation moved to).

CAS Number756875-51-1
PubChem CID11660192
IUPAC NameN-(1,3-dihydroxypropan-2-yl)-2-hexyl-3-oxodecanamide
Molecular FormulaC19H37NO4
Molecular Weight343.5
XLogP4.2
Topological Polar Surface Area86.6
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count16
Heavy Atom Count24
Formal Charge0
Complexity329
SMILES
CCCCCCCC(=O)C(CCCCCC)C(=O)NC(CO)CO
InChI
InChI=1S/C19H37NO4/c1-3-5-7-9-11-13-18(23)17(12-10-8-6-4-2)19(24)20-16(14-21)15-22/h16-17,21-22H,3-15H2,1-2H3,(H,20,24)
InChIKey
CGYVFCHCRBGGJG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Dihydroxyisopropyl capryloylcaprylamide
CAS: 756875-51-1
CID: 11660192
Formula: C19H37NO4
MW: 343.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight343.5
XLogP34.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count16
Exact Mass343.27225866
Monoisotopic Mass343.27225866
Topological Polar Surface Area86.6 Ų
Heavy Atom Count24
Formal Charge0
Complexity329
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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