4′,5′-Didehydro-5′-deoxy-5-methyluridine

4′,5′-Didehydro-5′-deoxy-5-methyluridine

• CAS Number: 1446748-33-9
• UNSPSC Description: 4′,5′-Didehydro-5′-deoxy-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/4-5-didehydro-5-deoxy-5-methyluridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(C)=C1)NC(N1[C@@H]([C@H](O)[C@@H]2O)OC2=C)=O
• Molecular Weight: 240.21
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported