DprE1-IN-11

• UNSPSC Description:

  DprE1-IN-11 (compound 3) is an orally active DprE1 inhibitor with antituberculosis activity against MTB H37Rv and MDR-MTB strains (MIC [1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/dpre1-in-11.html

• Smiles:

  NCCO/N=C1CCC(CC\1)CN2CCN(CC2)C3=NC(C4=CC(C(F)(F)F)=CC([N+]([O-])=O)=C4S3)=O

• Molecular Weight:

  528.55

• References & Citations:

  [1] Zhong X, et al. Design, synthesis and antimycobacterial activity of novel benzothiazinones with improved water solubility. Eur J Med Chem. 2024 Sep 3;279:116829.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported