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DprE1-IN-14

CAT: 0804-HY-179383Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179383Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DprE1-IN-14 (Compound 77) is a DprE1 inhibitor, with an IC50 value of 2.5 nM for M. tuberculosis. DprE1-IN-14 exhibits anti-tuberculosis activity, with an MIC₉₀ of 0.3 μM for the M. tuberculosis mc26230 strain. DprE1-IN-14 mainly shows bacteriostatic activity, demonstrating a time-dependent bactericidal effect at 10-fold MIC concentrations. DprE1-IN-14 can be used in anti-tuberculosis research[1].
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C(NCC1=CC=C(C2=CC=C(F)C=C2)N=C1)C3=NC([N+]([O-])=O)=CC=C3
Molecular Formula
C18H13FN4O3
Molecular Weight
352.32
References & Citations
[1]Thompson AM, et al. Advancing the antituberculosis activity of nitropicolinic acids and amides. Eur J Med Chem. 2026 Jan 15;302 (Pt 2) :118324.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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