PPARγ agonist 5

• Description :

  PPARγ agonist 5 (Compound 1) is a potent and selective agonist of PPARγ. PPARγ agonist 5 has the potential for the research of cancer diseases[1].

• CAS Number :

  [915124-86-6]

• UNSPSC :

  12352005

• Target :

  PPAR

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/pparγ-agonist-5.html

• Purity :

  98.59

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(N)=O)C5=NC6=C(N5C)C=CC=C6)C

• Molecular Formula :

  C33H31N5O

• Molecular Weight :

  513.63

• References & Citations :

  [1]Schoepf AM, et al. Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells. Eur J Med Chem. 2020 Jun 1;195:112258.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported