BTA-2

• Description :

  BTA-2, a benzothiazole dye, is structurally similar to thioflavin T (ThT), which exhibits an enhanced fluorescence signal when bound to amyloid fibrils. BTA-2 has distinct absorption and emission characteristics in solution and when bound to amyloid fibrils, which makes it can used for identifying amyloid fibrils using spectroscopy[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Amyloid-β

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/bta-2.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CC=C2N=C(C3=CC=C(C=C3)N(C)C)SC2=C1

• Molecular Formula :

  C16H16N2S

• Molecular Weight :

  268.38

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

• References & Citations :

  [1]Catherine C Kitts, et al. A spectroscopic study of 2-[4'- (dimethylamino) phenyl]-benzothiazole binding to insulin amyloid fibrils. J Fluoresc. 2010 Jul;20 (4) :881-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [10205-62-6]