BTA-EG4

CAT: 0804-HY-153889Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-153889Size:1 Each
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Description
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance the neurotoxicity of amyloid peptides in catalase-overexpressing neuronal cells, and can be used in the study of neurodegenerative diseases[1].
CAS Number
[921193-28-4]
UNSPSC
12352005
Target
Amyloid-β; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bta-eg4.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C2N=C(C3=CC=C(NCCOCCOCCOCCO)C=C3)SC2=C1
Molecular Formula
C22H28N2O4S
Molecular Weight
416.53
References & Citations
[1]Amrutha Chilumuri, et al. Benzothiazole Aniline Tetra (ethylene glycol) and 3-Amino-1,2,4-triazole Inhibit Neuroprotection against Amyloid Peptides by Catalase Overexpression in Vitro.Amrutha Chilumuri, Mark Odell, and Nathaniel G. N. Milton.ACS Chemical Neuroscience 2013 4 (11), 1501-1512.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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