BTA-1

• Description:

  BTA-1 is an uncharged derivative of thioflavin-T. BTA-1 has a high affinity for Aβ fibrils and shows very good brain penetration and clearance[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Amyloid-β

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bta-1.html

• Purity:

  98.30

• Solubility:

  10 mM in DMSO

• Smiles:

  CNC1=CC=C(C=C1)C2=NC3=CC=CC=C3S2

• Molecular Formula:

  C14H12N2S

• Molecular Weight:

  240.32

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Klunk WE, et al. The binding of 2- (4'-methylaminophenyl) benzothiazole to postmortem brain homogenates is dominated by the amyloid component. J Neurosci. 2003;23 (6) :2086-2092.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [439858-28-3]