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Ro 63-0563

CAT: 0804-HY-120239Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120239Size:1 Each
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Description
Ro 63-0563 is a potent, competitive and selective 5-HT6 receptor antagonist with pKi values of 7.83 and 7.91 for rat and human 5-HT6 receptors, respectively. Ro 63-0563 has no affinity for other receptors[1].
CAS Number
202466-77-1
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro-63-0563.html
Smiles
O=S(C1=CC=C(C=C1)N)(NC2=CC(NC)=NC(NC)=C2)=O
Molecular Formula
C13H17N5O2S
Molecular Weight
307.37
References & Citations
[1]Sleight A J, et al. Characterization of Ro 04‐6790 and Ro 63‐0563: potent and selective antagonists at human and rat 5‐HT6 receptors[J]. British journal of pharmacology, 1998, 124 (3) : 556-562.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor; MUC2

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