PD-321852

• UNSPSC Description:

  PD-321852 is a Chk1 inhibitor, with IC50 of 5 nM. PD-321852 can be used in anti-cancer research[1].

• Target Antigen:

  Checkpoint Kinase (Chk)

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pd-321852.html

• Smiles:

  O=C1NC(C2=C(C3=C(N4CCCNC)C=CC(O)=C3)C4=CC(C5=C(Cl)C=CC=C5Cl)=C21)=O

• Molecular Weight:

  468.33

• References & Citations:

  [1]Parsels LA, et al. Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells. Mol Cancer Ther. 2009 Jan;8(1):45-54.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  622856-21-7