PD-321852

CAT: 0804-HY-124731Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-124731Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PD-321852 is a Chk1 inhibitor, with IC50 of 5 nM. PD-321852 can be used in anti-cancer research[1].

CAS Number

622856-21-7

UNSPSC

12352005

Target

Checkpoint Kinase (Chk)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pd-321852.html

Smiles

O=C1NC(C2=C(C3=C(N4CCCNC)C=CC(O)=C3)C4=CC(C5=C(Cl)C=CC=C5Cl)=C21)=O

Molecular Formula

C24H19Cl2N3O3

Molecular Weight

468.33

References & Citations

[1]Parsels LA, et al. Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells. Mol Cancer Ther. 2009 Jan;8 (1) :45-54.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Chk1

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