PD-321852

CAT: 0013-GTR19210956-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19210956-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PD-321852 is a selective Chk1 inhibitor that enhances gemcitabine cytotoxicity in pancreatic cancer models, as demonstrated by in vitro studies showing synergistic chemosensitization and loss of Chk1 protein. This compound is a valuable research tool for investigating DNA damage response pathways and combination chemotherapy strategies.

CAS Number

622856-21-7

Field of Research

Cell Biology

Smiles

C (CCNC) N1C2=C (C3=C (C (=C2) C4=C (Cl) C=CC=C4Cl) C (=O) NC3=O) C=5C1=CC=C (O) C5

Molecular Formula

C24H19Cl2N3O3

Molecular Weight

468.33

Storage Conditions

-20°C

Notes

For research use only.

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