PD-1/PD-L1-IN-19

• UNSPSC Description:

  PD-1/PD-L1-IN-19 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-19 blocks PD-1/PD-L1 with the IC50 of 62.3 nM. PD-1/PD-L1-IN-19 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].

• Target Antigen:

  PD-1/PD-L1

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pd-1-pd-l1-in-19.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=CC=CC(COC2=CC(OCC3=CC=CC(C4=CC=CC=C4)=C3Br)=C(C=C2CNCCNC(C)=O)Cl)=C1

• Molecular Weight:

  618.95

• References & Citations:

  [1]Benzyl phenyl ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202273A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2156651-18-0